| Primary
Name |
Factor
II Assay |
| Synonym |
Prothrombin
Assay |
| Synonym |
Factor
II Functional Assay |
| Contraction |
FII |
| Contraction |
-- |
| Contraction |
-- |
| UAB
Procedure Number |
2500470 |
| CPT
Code |
85210 |
| Specimen |
Collect
one (1) blue-stopper tube (3.2% sodium citrate), filled to specified
volume. Do not underfill or overfill.
|
| Specimen
Management |
Note
time of collection and time of last treatment if applicable.
Centrifuge blue-stopper tube within 1 hour of collection,
separate plasma and test or quick-freeze at -70°C. |
| Specimen
Accepted |
Daily
including weekends |
| Times
Available |
0730-1600;
deliver to lab by 1300 for same-day results |
| Test
Performed |
Monday-Friday. |
| Available
Stat? |
Pathologist's
approval required. |
| Description |
Congenital
factor II (prothrombin) deficiency is caused by one of several rare mutations
that reduce prothrombin production or activity. Acquired prothrombin deficiency
is caused by vitamin K deficiency, the use of Coumadin therapy, or prothrombin-neutralizing
lupus anticoagulant. |
| Reference
Interval |
50-150% |
| Critical
Value |
-- |
| Therapeutic
Range |
-- |
| Follow-up
Test |
If
the functional prothrombin assay indicates a deficiency, the prothrombin
antigen assay may be used to distinguish qualitative from quantitative
disorders. |
| Associated
With |
Bleeding
disorders |
| Associated
With |
Lupus
anticoagulant |
| Associated
With |
Vitamin
K deficiency |
